Nitrosigine: A Powerful Nitric Oxide Booster

Nitrosigine: A Powerful Nitric Oxide Booster

Nitric oxide (NO) is a signaling molecule that plays a crucial role in various bodily functions, including cardiovascular health, blood flow, and cognitive function. In the realm of sports nutrition, NO is highly sought after for its ability to enhance vasodilation, improve muscle pumps, and boost exercise performance. Among the various NO boosters available, Nitrosigine has emerged as a promising contender due to its unique properties and promising research backing.

What is Nitrosigine?

Nitrosigine, also known as inositol-stabilized arginine silicate, is a patented form of L-arginine, an amino acid that serves as a precursor to NO production. Unlike L-arginine, which breaks down rapidly in the digestive system, Nitrosigine's inositol-stabilized structure enhances bioavailability and prolongs its action in the body.

Benefits of Nitrosigine

Nitrosigine offers a range of benefits, including:

  1. Enhanced Nitric Oxide Production: Nitrosigine effectively increases NO levels, leading to improved blood vessel dilation and blood flow.

  2. Improved Muscle Pumps and Exercise Performance: Increased blood flow to working muscles delivers more oxygen and nutrients, enhancing muscle performance and reducing fatigue.

  3. Cognitive Enhancement: Nitrosigine has shown promising effects on cognitive function, including improved focus, memory, and mental alertness.

Comparison with Citrulline

Citrulline is another popular NO booster, often compared to Nitrosigine. Citrulline converts to L-arginine in the kidneys, eventually increasing NO production. While citrulline is effective, Nitrosigine offers several advantages:

  1. Superior Bioavailability: Nitrosigine's inositol-stabilized structure ensures better absorption and utilization compared to L-arginine or citrulline.

  2. Faster NO Production: Nitrosigine directly elevates NO levels, bypassing the conversion step required for L-arginine or citrulline.

  3. Prolonged NO Elevation: Nitrosigine's effects on NO production are more sustained compared to citrulline.

Recommended Dosage of Nitrosigine

Research suggests that a dosage of 1.5-3 grams of Nitrosigine is effective for enhancing NO production and exercise performance. It is typically consumed 30-60 minutes before exercise.


Nitrosigine has emerged as a powerful NO booster with a range of potential benefits, including improved blood flow, enhanced exercise performance, and cognitive support. Its superior bioavailability and prolonged NO elevation set it apart from other NO boosters like citrulline. With a recommended dosage of 1.5-3 grams, Nitrosigine can be a valuable addition to the pre-workout regimen of athletes and individuals seeking to optimize their performance.

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